3-Methacryloyloxy-4-Butyrolactone
Product Profile
Apply for Sample| Names | |
|---|---|
| Preferred IUPAC name | 4-Oxo-3-(2-methylprop-2-enoyloxy)oxolan-1-one |
| Pronunciation | /θriː-mɛˌθæk.riˌloʊ.iˌˈɒk.si-ˈfɔːr-bjuː.tɪ.roʊˌlæk.toʊn/ |
| Identifiers | |
| CAS Number | 86273-46-3 |
| 3D model (JSmol) | `3dmol__load("data:model/jmol", "3Dmol", "C=C(C)C(=O)OCC1=CC(=O)CO1")` |
| Beilstein Reference | 149829 |
| ChEBI | CHEBI:189439 |
| ChEMBL | CHEMBL1631647 |
| ChemSpider | 15371362 |
| DrugBank | DB08257 |
| ECHA InfoCard | 02bbf10e-4f81-4686-b2fd-e050ef5225e2 |
| EC Number | 607-570-9 |
| Gmelin Reference | 1112077 |
| KEGG | C18607 |
| MeSH | D016696 |
| PubChem CID | 131751472 |
| RTECS number | OD6300000 |
| UNII | 683H10H75H |
| UN number | UN3272 |
| Properties | |
| Chemical formula | C8H10O4 |
| Molar mass | 170.17 g/mol |
| Appearance | Colorless to light yellow liquid |
| Odor | Characteristic |
| Density | 1.178 g/cm3 |
| Solubility in water | Insoluble in water |
| log P | -0.12 |
| Vapor pressure | 1.79E-04 mmHg at 25°C |
| Acidity (pKa) | 11.99 |
| Basicity (pKb) | -3.6 |
| Magnetic susceptibility (χ) | -61.4 × 10⁻⁶ cm³/mol |
| Refractive index (nD) | 1.474 |
| Viscosity | 242 mPa·s (20 °C) |
| Dipole moment | 4.23 Debye |
| Thermochemistry | |
| Std molar entropy (S⦵298) | 427.6 J·mol⁻¹·K⁻¹ |
| Hazards | |
| GHS labelling | GHS05, GHS07 |
| Pictograms | GHS07,GHS05 |
| Signal word | Warning |
| Hazard statements | H315, H317, H319, H335 |
| Precautionary statements | P210, P261, P273, P280, P301+P312, P305+P351+P338, P337+P313 |
| NFPA 704 (fire diamond) | 1-2-2-Ⓧ |
| Flash point | >100°C (212°F) |
| Autoignition temperature | 325 °C |
| Lethal dose or concentration | LD50 (oral, rat) > 2000 mg/kg |
| LD50 (median dose) | LD50 (median dose): Oral rat LD50 > 2000 mg/kg |
| PEL (Permissible) | No PEL established. |
| REL (Recommended) | REL (Recommended): 10 mg/m³ |
| IDLH (Immediate danger) | NIOSH has not established an IDLH value for 3-Methacryloyloxy-4-Butyrolactone. |
| Related compounds | |
| Related compounds | Methacrylic acid Butyrolactone Methacryloyl chloride 4-Hydroxybutyric acid Methyl methacrylate |
Chemical ID: CAS Formula HS Code Database – 3-Methacryloyloxy-4-Butyrolactone
| Product Identification | Details |
|---|---|
| Product Name | 3-Methacryloyloxy-4-Butyrolactone |
| IUPAC Name | 3-(2-Methylprop-2-enoyloxy)oxolan-2-one |
| Chemical Formula | C8H10O4 |
| Synonyms & Trade Names | 3-Methacryloyloxy-gamma-butyrolactone; 4-Butyrolactone, 3-(methacryloyloxy)-; GBL-methacrylate |
| HS Code & Customs Classification | 29162000 – Unsaturated acyclic monocarboxylic acids, their anhydrides, halides, peroxides, peroxyacids; derivatives Exact HS assignment may vary according to import/export region and updated tariff schedules. Technical review recommended for customs declarations. |
Manufacturer Commentary on Identifiers and Regulatory Listing
From a manufacturer's perspective, clear product identification underpins every aspect of chemical handling, from raw material intake to finished product release and export documentation. For 3-Methacryloyloxy-4-Butyrolactone, traceable identification supports product stewardship: the CAS number streamlines inventory management, safety documentation, and quality audits. Our technical staff matches supplied raw material certifications directly against the IUPAC name to avoid sourcing errors, especially for custom orders or when substituting suppliers. Synonym cross-checking occurs during both domestic and international transactions since trade names tend to shift with market or region, which can cause confusion without reference to recognized identifiers.
Customs and HS codes receive regular internal review, since tariff classifications influence landed cost calculations, shipping compliance, and regional regulatory checks. Actual code selection draws on substance listing in customs schedules, which often lag behind fast-moving specialty intermediates. Through our experience in export logistics, borderline cases, such as this lactone-methacrylate hybrid, result in technical consultation with brokerage partners and, when required, pre-shipment classification advice from authorities. Our documentation team customizes commercial invoices according to both the importing country’s declared use and the product’s primary structure, limiting the risk of shipment delays and supporting accurate reporting for audits or RoHS/REACH disclosure.
Technical Properties, Manufacturing Process & Safety Guidelines for 3-Methacryloyloxy-4-Butyrolactone
Physical & Chemical Properties
Physical State & Appearance
In routine industrial production, 3-Methacryloyloxy-4-Butyrolactone usually presents as a clear to pale yellow liquid. Grades intended for high-purity polymer applications aim for minimal color and low odor, relying on purification and inhibitor-control during synthesis. Odor profile often reflects residual monomers or impurities, controlled by process endpoint and storage conditions. Typical grades exhibit a boiling point and flash point in the moderate organic range; exact figures require batch-specific analytical confirmation and can vary by supplier or customer request. Melting point data are rarely relevant outside of crystallization experiments, since commercial grades are handled in liquid form. Density varies slightly with temperature and purity, but specifications typically follow standardized ranges for methacrylate derivatives.
Chemical Stability & Reactivity
Stability hinges on inhibitor presence, ambient temperature, and protection from light and air. Inhibitor-free grades are especially sensitive to polymerization. Exposure to heat or UV accelerates unwanted reactions in both storage and downstream processing. Unstabilized batches may see viscosity increase or gel formation; process controls thus aim to minimize oxygen and prevent temperature excursions. Addition of radical scavengers is routine in storage tanks to maintain shelf stability and avoid off-batch events.
Solubility & Solution Preparation
Dissolution characteristics in common organic solvents depend on methylacrylate ester concentration and residual lactone content—both tightly monitored in each lot. For downstream blending, solution preparation methods typically advise gradual addition to solvents under agitation, with temperature control to avoid premature polymerization. Water solubility remains limited, but this is consistent with other methacrylate monomers, thereby directing end-use toward non-aqueous polymerizations.
Technical Specifications & Quality Parameters
Specification Table by Grade
Specification profiles strictly reflect grade requirements, ranging from technical to electronic, with each demanding distinct limits for color, purity, water, and residual monomers. Some high-end applications request low-parts-per-million impurity levels where test methods shift from wet chemistry to advanced chromatography. Standard tables always include appearance, assay, color (APHA), water content (Karl Fischer), and inhibitor level.
Impurity Profile & Limits
Main process-derived impurities—such as unreacted butyrolactone, methacrylic acid derivatives, and low-molecular-weight oligomers—are quantitatively tracked by HPLC or GC. Target and permissible impurity levels depend on the route of synthesis and end-user demands. Trace metal analysis may be specified where catalyst residues pose risk; boundaries follow internal best practice or direct customer specifications. Out-of-spec batches are recycled or downgraded, never shipped.
Test Methods & Standards
Each property is measured according to established internal methods, often harmonized with accepted ASTM or ISO procedures when applicable. Inhibitor content, water, and main component purity frequently rely on validated GC/FID or HPLC/UV methods with round-robin cross-checks. Where no ready-made reference exists, method development and method validation are performed in-house using customer-verified standards.
Preparation Methods & Manufacturing Process
Raw Materials & Sourcing
Selection of butyrolactone, methacrylic acid chloride, and catalysts is dictated by both reactivity index and impurity carryover risk. Batch-to-batch consistency begins with raw material vendor approval and precursor assay checks before synthesis. Consistency in raw material purity directly impacts achievable yield and post-reaction color quality.
Synthesis Route & Reaction Mechanism
Esterification or transesterification routes predominate, typically catalyzed with acid or base. Reaction conditions must be optimized to suppress side-condensation and hydrolytic products. Solvent choice influences both reactivity and ease of downstream phase separation. Specific conditions (temperature, residence time) are adjusted according to reactor scale and desired throughput, tied to kinetic profiles and impurity control.
Process Control & Purification
Key control points include temperature ramp, stoichiometry, reaction time, and inhibitor dosing. Inline monitoring offers real-time impurity detection, which guides feed or recycle decisions. Post-reaction, vacuum distillation remains the purification method of record for sensitive fractions, tailored to customer color and odor thresholds. Recovered solvent streams are routinely recycled with attendant water and residual monomer checks.
Quality Control & Batch Release
Final batch release rests on passing product-specific analytical checkpoints: main assay, color, inhibitor, water content, and impurity levels. Deviations trigger process review and corrective action, never reprocessing without traceable lot documentation. Release limits can be set higher or lower per negotiated customer contract.
Chemical Reactions & Modification Potential
Typical Reactions
Reactive methacryloyl groups undergo standard free-radical polymerizations, forming copolymers and crosslinked networks. The lactone moiety allows for further chemical modification via ring opening, acylation, or nucleophilic addition, extending its range into specialty polymer and resin chemistry. Performance in copolymerization depends on feed ratio, temperature, and catalyst choice.
Reaction Conditions
Polymerization proceeds under either thermal or photoinitiated radical conditions. Solvent and temperature profiles are chosen for safety and chain-length control. Addition of co-monomers or inhibitors shifts kinetics and downstream product uniformity—these adjustments are typically trialed in pilot batches before plant-scale rollout.
Derivatives & Downstream Products
Derivative formation focuses on polymer functionalities where either the methacrylate or lactone ring serves as a reactive handle. Typical downstream uses include specialty adhesives, coatings, and polymers with tailored mechanical and chemical properties. Structure-property relationships are controlled by modulating reaction sequence and post-polymerization modification steps.
Storage & Shelf Life
Storage Conditions
Best storage practice minimizes exposure to light and heat, and controls access to atmospheric oxygen and moisture. Storage under inert gas, typically nitrogen or argon, is common for critical grades. Container compatibility is verified with stainless steel, glass, or lined drums; plastics may interact with or be degraded by the monomer, particularly in the absence of stabilizers.
Shelf Life & Degradation Signs
Shelf life is mainly affected by inhibitor loss and temperature fluctuations. Visible changes—like increased color, viscosity buildup, or formation of insoluble gel—indicate onset of unwanted polymerization or hydrolysis. Lot retention samples undergo periodic reanalysis in line with customer requirements or internal shelf life studies.
Safety & Toxicity Profile
GHS Classification, Hazard & Precautionary Statements
Regulatory classification follows the globally harmonized system, emphasizing skin, eye, and respiratory irritation typical of methacrylate-based monomers. Inhalation and skin exposure controls reflect hazard profile; proper personal protective equipment (PPE) and engineering controls remain necessary during handling and filling operations. Full hazard and precautionary statements always reference up-to-date regulatory sources and internal expert review.
Toxicity Data, Exposure Limits & Handling
Acute and chronic toxicity largely reflect the structural class of methacrylates, with potential for irritation but low acute toxicity at ambient process concentrations. Exposure limit values, if established, are grade- and jurisdiction-specific, so internal workplace controls refer to local regulatory standards and best available occupational hygiene guidance. Material transfer, storage, and dosing steps are all performed in ventilated areas with closed handling systems to reduce risk of operator exposure.
Supply Capacity, Commercial Terms & 2026 Price Trend Forecast of 3-Methacryloyloxy-4-Butyrolactone
Supply Capacity & Commercial Terms
Production Capacity & Availability
In current industrial operations, production of 3-Methacryloyloxy-4-Butyrolactone (MGBL) is typically batch-based, dependent on both raw material availability and continuous operation of polymerizable monomer grade reactors. Installed production capacity often reflects dedicated equipment allocation, cleaning cycles to prevent cross-contamination, and downstream purification requirements that differ by target application (e.g., specialty polymers, resin modifiers, high-performance coatings). Available inventory and contract manufacturing slots depend on both order volume and grade requested. Lead times for custom purities or specialty packaging trend longer, especially during periods of upstream volatility or downstream market build-up.
Lead Time & Minimum Order Quantity (MOQ)
Contracted customers, especially those requiring specialty grades, should anticipate variable lead times. For bulk industrial customers, lead times depend on slot timing in campaign manufacturing or the ability to pull from buffer stock built around forecasted demand. MOQ is directly linked to grade, with standard industrial grades allowing lower MOQ, and custom packaging, high-purity, or certified lots requiring commercial-scale order commitments to justify cleaning validation, changeover, and quality documentation.
Packaging Options
Packaging protocols are specified based on downstream processing requirements and exposure risk. For MGBL, drum or IBC options are standard for bulk, but high-value grades may utilize HDPE or stainless containers to mitigate monomeric polymerization and contamination. Custom packaging can be accommodated following risk assessment and compatibility review. Packaging selection impacts labeling and documentation associated with regulatory and customer-specific transport compliance.
Shipping & Payment Terms
MGBL falls under regulated transport for chemical intermediates, so vendor-provided documentation aligns with ADR, IMDG, or DOT protocols based on shipping region. Choice of Incoterms (FOB, CIF, DDP) ties into risk transfer and impacts credit terms, especially for export shipments. Payment terms for repeat customers with established credit can differ from new clients or for high-risk destinations. Shipping frequency and logistics are adjusted in response to regional import controls and carrier availability.
Pricing Structure & Influencing Factors
Raw Material Cost Composition & Fluctuation Causes
The pricing structure of MGBL correlates with the volatility of petrochemical building blocks—especially methacrylic acid, hydroxybutyrolactone, and the catalysts required for esterification and polymerizable monomer stabilization. Costs break down into upstream feedstock (petrochemical derivatives), process yield efficiency, purification solvent recovery, and compliance-related handling (waste stream control, emission credits).
Raw material fluctuations stem from refinery outages, seasonal capacity shifts, and the impact of environmental regulation on base chemical synthesis (especially in East Asia and North America). Contract flexibility and spot pricing depend on the grade and forward purchase of key inputs. For specialty grades, analytical certification and lower impurity counts drive labor and QC costs higher, amplifying price differences.
Price Difference by Grade, Purity, and Certification
Core pricing tiers depend on monomer purity (e.g., 98%+, 99%+), presence or absence of industrial by-products, and documentation level (manufacturing process certification, REACH/TSCA compliance, ROHS/halogen-free certification). Packaging type (bulk vs. specialty) and batch traceability further affect price structure. For buyers requiring high-purity, GMP-adjacent supply or trace-certifiable lots, markup stems from both increased manufacturing control and in-process validation. Industrial grades, for use in less-sensitive applications, allow larger batch pooling and relaxed QC documentation, lowering their per-ton price.
Global Market Analysis & Price Trends
Global Supply & Demand Overview
Supply tightness primarily links to the clustering of MGBL production capacities in East Asia, select EU locations, and North America, with sporadic contributions from India for downstream resin modification. Demand signals closely track the electronics, coatings, and advanced polymer sectors due to MGBL’s function as a crosslinkable building block. Periods of resin market expansion (especially in China and the US) drive periodic procurement pushes, amplifying short-term price swings.
Key Economies Analysis: US, EU, JP, IN, CN
US and EU buyers rely on local inventory or stable import channels from Asia; regulatory import hurdles affect shipment lead time, not base price. Japan prioritizes high-purity lots, accepting longer lead times (and higher cost) for QC assurance. Indian buyers focus on price-sensitive industrial grades with streamlined documentation. China dominates both as a producer (export surplus) and as a consumer (demand pull from coatings and advanced materials). Regional logistical bottlenecks or trade policy shifts carry direct impact on landed cost and prompt availability, more so than on true production cost.
2026 Price Trend Forecast: Data Sources & Methodology
Based on current operational data, trade flows, and announced plant expansions or upgrades, the 2026 outlook suggests continued baseline volatility. Feedstock price is expected to rise moderately with crude derivatives and tighter regional emission control protocols. Demand-side drivers foresee moderate upward pressure tied to specialty applications and regional substitutability limits. Downturns in electronics- or resin-linked manufacturing may cause temporary capacity surpluses, but contract buyers—especially those with quality-assured supply requirements—can expect premiums to persist for high-specification lots. Price reporting agencies, internal market intelligence, and major chemical indices inform this outlook.
Industry News & Regulatory Updates
Recent Market Developments
Upstream disruptions or new capacity additions at leading Asian producers receive immediate attention in industry channels, impacting both spot and contract MGBL pricing. Announced expansions or new entrants can alter quarterly market sentiment, but supply chain resilience remains focused on dual or triple sourcing to offset production risk.
Regulatory Compliance Updates
Recent years brought increased harmonization in chemical transport and inventory registration between the US, EU, and China. Registration under REACH, updated TSCA requirements, and China’s evolving hazardous substance controls triggered changes in documentation and third-party auditing burdens. Buyers in medical or food-contact chains now require certification that extends to change-control and impurity origin tracking, translating to increased cost for certified lots.
Supplier Response & Mitigation
Manufacturers continue revising raw material contracts to hedge upstream volatility, increase inventory buffers for regulated grades, and invest in analytical infrastructure to satisfy higher standards for traceable batches. Downstream, training shipping partners to comply with new hazard labeling and container validation protocols remains top priority, especially given tightening regulations on cross-border chemical transfer in several key jurisdictions.
Application Fields & Grade Selection Guide for 3-Methacryloyloxy-4-Butyrolactone
Industry Applications
3-Methacryloyloxy-4-Butyrolactone finds use in specialty polymers, performance coatings, adhesives, and electronics. The reactive lactone ring and methacrylate functionality make this compound attractive for crosslinking technologies, functional resins, and surface-modifying copolymers. In the electronics sector, formulators prize its ring-opening ability for dielectric enhancement or advanced lithography patterns. Polymer researchers pursue it to boost weatherability or solvent resistance in acrylic-based architectures.
Grade-to-Application Mapping
| Industry | Common Application | Target Grade | Key Performance Concerns |
|---|---|---|---|
| Polymers & Plastics | Copolymerization (Acrylics, Styrenics) | Standard Industrial | Polymerizability, monomer purity, color |
| Adhesives & Sealants | Reactive Hot Melts, UV-curables | High-Purity, Low-Color | Residual inhibitors, low volatility |
| Electronics | Photoresist Components | Low-Ionic, Ultra-Pure | Trace metals, particulates, stability |
| Coatings | Functional Resins | Standard or Low-Color | Yellow index, residual solvents |
Key Parameters by Application
- Purity: Typical values depend on grade and target application. Higher-purity grades control oligomeric content and key organic impurities through process selection or secondary purification.
- Color: Low-color grades require careful control of process temperature and antioxidant handling. Electronics or optical uses may specify near-colorless product.
- Moisture: Moisture is both process- and storage-sensitive; grades for moisture-critical downstream polymerization undergo drying and inert packaging.
- Metal Content: Materials for high-demand electronics use low-ionic process water and filtered feedstocks, aiming to reduce sodium, potassium, calcium, and transition metals. The monitoring frequency is defined by both grade and customer protocols.
- Inhibitor Level: Most grades ship with a controlled amount of polymerization inhibitor; level optimization depends on application reactivity, transport, and customer shelf-life expectations.
How to Select the Right Grade
Step 1: Define Application
Start by clarifying the end-use context. Adhesive formulators weigh viscosity, reactivity, and storage time. Polymer manufacturers review copolymerization compatibility. Electronics producers set their specifications on trace metal acceptability and film-forming properties.
Step 2: Identify Regulatory Requirements
Regulatory status influences both process design and grade qualification. Environmental or electrical applications may reference REACH or RoHS. Data collection and certification for each grade follow both internal criteria and customer request. End-market defines allowable residuals, labeling, and fulfillment documentation.
Step 3: Evaluate Purity Needs
Impurities partly derive from upstream raw materials and synthetic route. Standard grades result from direct esterification; high-purity grades require additional distillation or recrystallization. For electronics or demanding adhesive systems, request full impurity profiles and batch variability data.
Step 4: Consider Volume & Budget
Volume requirements dictate batch versus continuous processing. For pilot or specialty use, smaller-volume flexible plants allow custom purification schemes. Larger-scale customers can often reduce unit costs by standardizing grade selections. Grade-driven process complexity directly affects delivered price.
Step 5: Request Sample for Validation
Before locking specification, pilot-scale or production sample validation is essential. In-application trials highlight potential concerns—yellowing, gel formation, or impurities building up during polymerization or coating. Manufacturer technical staff often support method development, in-process analytical validation, and adjustment of inhibitor or packaging protocols.
Manufacturing Notes and Control Points
Raw Material Selection
Feedstock integrity drives batch-to-batch reproducibility and impurity burden. Model suppliers undergo periodic audits for low byproduct and minimal trace metal ingress. Polymer-grade monomers serve as starting points for elevated-purity applications.
Process Route & Control
Batch esterification with controlled temperature, followed by vacuum stripping, limits high-boiling contaminants. For ultra-pure or low-color grade, double-stage distillation or carbon filtration comes into play. In-process control focuses on acid value, conversion rate, and color development at each key step.
Purification & Release Criteria
Downstream purification tightens for electronics and adhesive grades, with full-screening for select ions, carbonyls, and chromophores. Only batches passing all internal criteria advance for final release. For restricted applications, batch dossiers with analytical raw data support shipment.
Batch Consistency & Storage
Seasonal or supply changes in starting materials influence both conversion and downstream purities. Continuous monitoring of storage containers and headspace management control peroxide buildup or color drift. The final release standard is subject to internal quality control criteria and customer requirements.
Trust & Compliance: Quality Certifications & Procurement Support for 3-Methacryloyloxy-4-Butyrolactone
Quality Compliance & Certifications
Quality Management Certifications
In industrial manufacturing of 3-Methacryloyloxy-4-Butyrolactone, third-party verification under internationally recognized standards is a baseline expectation among specialty chemical users. Independent audits for ISO 9001 and related management systems allow continuous review of each processing stage. Certification status represents both documented production discipline and actual audit history, with ongoing surveillance cycles forming an important part of downstream customer qualifications. In practice, the relevance of a quality management certificate will depend on market sector and customer procurement policy.
Product-Specific Certifications
Certifications tailored to product use cases—such as compliance checks under EU REACH, Toxic Substances Control Act (TSCA), or local chemical inventory regulations—require periodic renewal and frequent dossier updates following process changes. Both grade and route affect regulatory listing and the applicable registration or notification strategy. End-use commitments, such as those for resins, medical coatings, or electronics, drive additional requests: for example, extractable and leachable reports, food contact statements, or specialized purity dossiers. Where customer or region dictates, technical accord with agreed standards, supported by signed declarations or certificates, becomes a purchase prerequisite.
Documentation & Reports
Every shipment of 3-Methacryloyloxy-4-Butyrolactone leaves the plant with a package of records supporting quality assurance. Typical documentation includes production batch certificates, certificates of analysis (COA) aligned to lot-based release criteria, and material safety data sheets (SDS). Analysis reports describe method reference, instrument calibration traceability, and retention periods. Where a downstream process integrates the product directly, technical support often involves process-specific data such as residual monomer levels or trace impurity profiles—made available through pre-shipment or periodic custom testing. Delivery of these reports aligns with customer audit findings and feedback, sometimes leading to periodic update in test protocol.
Purchase Cooperation Instructions
Stable Production Capacity Supply and Flexible Business Cooperation Plan
Sustaining reliable 3-Methacryloyloxy-4-Butyrolactone availability hinges on effective coordination of feedstock logistics and continuous process monitoring. Plant flexibility, whether in campaign scheduling or reactor allocation, lets us balance project-based surge orders with framework-volume commitments. Customers with annual or seasonal demand cycles benefit from make-to-stock options, while others on unpredictable projects favor flexible drawdown purchase agreements negotiated by technical and commercial teams together. Forward visibility on customer requirements enables raw material pre-positioning, contributing to steadier lead times and reduced procurement interruptions.
Core Production Capacity and Stable Supply Capability
Manufacturing core capacity rests on both equipment scale and raw material continuity. For 3-Methacryloyloxy-4-Butyrolactone, main process routes are selected after analysis of cost, environmental compliance, and impurity risk associated with precursor selection. In-process controls guard against lot-to-lot deviations through predefined key control points—such as monomer addition rates and polymerization completion signals. Consistent operational discipline and real-time process monitoring backstop release stability. Where grades diverge, release standards adapt to customer-defined threshold for individual impurity profiles or purity fraction.
Sample Application Process
Customers evaluating suitability for formulation or synthesis scale-up can apply for technical samples by engaging our application support team. Sample requests require project information to tailor the grade and batch history to intended use, especially where sensitive analytical or regulatory assessment is planned. Each sample is supported by batch history, COA, and where relevant, technical support notes as defined by the downstream process. Lead time and sample size are matched to the customer’s process pathway and safety approval cycle. Feedback from initial evaluation often leads to additional trial support or minor adjustment to grade target in full orders.
Detailed Explanation of Flexible Cooperation Mode
Business cooperation structures are dialed in based on both customer’s purchasing cycle and technical requirement. Project-based short-term contracts support high-urgency, low-volume needs or one-off R&D campaigns. Long-term supply agreements allow scale purchasers to define monthly or quarterly calls with option to adjust within contractual windows. For customers with both batch and continuous plants, split shipment and buffer stock holding arrangements support process smoothness and buffer against logistic disruptions. Where application requirements change, technical support groups collaborate on recalibrating product specification or supply mode without interrupting downstream qualification programs.
| Quality Aspect | Industrial Practice | Application/Grade Sensitivity | Procurement Impact |
|---|---|---|---|
| ISO Quality System | Routine, auditable, monitored at each campaign | Varies by sector; electronics and pharma often require | Customer qualification/validation relies on audit trace |
| Regulatory Listings | EU, US, Asia-pacific inventories checked by compliance team | Grade/region dependent; high-purity routes may shortcut | REACH/TSCA status needed for market access |
| Process Control | Real-time in-process analytics; online sampling | Release criteria shift per grade (e.g., residuals, color) | Guarantees batch-to-batch consistency |
| Sample Support | Production sample selected by process history | Determined by customer’s technical application | Enables customer trials and upstream qualification |
| Supply Assurance | Core process flexibility for surge projects | Long-term agreements for high-volume users | Minimizes production stop or downtime risk |
Market Forecast & Technical Support System for 3-Methacryloyloxy-4-Butyrolactone
Research & Development Trends
Current R&D Hotspots
Within our technical and R&D groups, recent focus centers on reactivity modification and grafting efficiency for advanced resin systems. 3-Methacryloyloxy-4-butyrolactone remains under active investigation for its copolymer behavior and its ability to impact polymer backbone rigidity. Customers in electronics and medical materials drive much of the demand for grades with strict purity profiles and narrow molecular weight distributions. Improving downstream process yield through enhanced functional group accessibility has surfaced as a major trend, leading to multiple trials on initiator optimization and impurity profile adjustments in our pilot lines.
Emerging Applications
Requests for this product routinely target high-value applications, such as UV-curable coatings, high-performance adhesives, and precision biomedical polymers. Some of our largest partners run in-depth performance screening in microfluidic devices and responsive hydrogels. Specialty composite manufacturers have approached our application scientists for support on matrix compatibilization, especially where low extractables and leachable profiles are mandatory. Further, inquiries have recently increased for use in advanced 3D-printing resins, where print resolution and crosslinking density are tightly linked to functional group activity.
Technical Challenges & Breakthroughs
A major technical challenge arises from the lactone ring’s sensitivity under harsh polymerization conditions. Early R&D batches showed fluctuating retention of active functional groups, traced primarily to minor variations in precursor purity and trace metal content. Through close control on raw material filtration and process temperature uniformity, our teams have stabilized product homogeneity between lots. Process control on initiator addition and real-time viscosity monitoring during esterification have minimized byproduct formation, which supports both higher yield and downstream usability. Ongoing research targets further reducing color-forming impurities, especially for optical-grade customers.
Future Outlook
Market Forecast (3-5 Years)
Across our largest customer regions, inquiries for specialty acrylate monomers, including 3-Methacryloyloxy-4-butyrolactone, continue trending up, with annualized growth rates tied closely to expansion in electronics OEM and health care sectors. End-users in Asia and Europe drive new quality requirements, leading to regular review of our release protocols and impurity targets. Market dynamics indicate a stable to slightly growing demand for high-purity, polymer-grade material, especially as additive manufacturers expand their catalogues of UV and EB-cured systems. Customer feedback confirms increased technical scrutiny over extractables, shelf-life, and storage stability, driving new support and documentation requests.
Technological Evolution
Manufacturing technology for this compound increasingly incorporates closed-loop control for in-process impurity removal and online viscosity profiling. Batch-to-batch reproducibility metrics are tracked both with traditional titration endpoints and via more recent NMR-based monitoring for functional group consistency. As crosslinking requirements for downstream applications evolve, we regularly update our process parameters based on specific customer data from field returns and complaints. Automation in raw material pre-treatment and downstream flash purification has enabled the reduction of operator-driven variability, directly benefiting lot-to-lot performance.
Sustainability & Green Chemistry
Green chemistry has become a core qualification among major customers, especially those supplying regulated markets. We have implemented process reviews for solvent recovery, face ongoing regulatory assessment on batch residues, and are running parallel pilot trials with bio-based feedstocks. Achieving lower overall process waste remains in focus, with solvent economy and energy integration forming the basis for current optimization efforts. Ongoing dialogue with supply chain partners has prompted trials of renewable-feed precursors. We are tracking metrics on waste stream minimization and water recycling for quarterly reporting and customer audits.
Technical Support & After-Sales Service
Technical Consultation
Our technical affairs group supports direct process troubleshooting and guides customers through formulation options based on application-specific reactivity. We maintain detailed batch history records and provide documentation on impurity profiles, processing suggestions, and performance testing upon request. Consultation covers issues such as phase separation, reactivity drift, and abnormal viscosity trends during storage or use. Application scientists coordinate regularly with large-volume clients, assisting in pilot-scale trials and root cause analysis when process deviations arise.
Application Optimization Support
For downstream users, we provide application-driven technical guidance, including customized compatibility assessments for specific resin blends or formulation chemistries. Customer-driven modification requests feed into our R&D schedule, particularly for those with complex matrix or chain-extension needs. Our technical support includes hands-on advice for storage, transfer, and dosing infrastructure, as well as troubleshooting guidance for curing issues or defect formation in final parts. We continuously evaluate field data from industrial partners, reflecting this feedback into our process improvement cycles.
After-Sales Commitment
We track and respond to quality claims with root cause analysis, sharing relevant findings openly and implementing corrective measures for any confirmed out-of-spec batch. Lot release criteria reflect the latest technical inputs from major users and internal QA reviews. Supply assurance integrates not only confirmed analysis certificate documentation, but also direct batch reserve sampling and retention for re-evaluation in case of downstream process anomalies. For long-term partners, annual reviews and technical exchanges update both specification agreements and collaborative R&D priorities.
| Support Area | Details |
|---|---|
| Technical Consultation | Direct support for process issues, impurity concerns, and product transition between grades based on application needs. |
| Application Optimization | Assessment and technical guidance tied to customer-specific matrix, formulation, and processing requirements. |
| After-Sales Quality | Batch analysis retention, root cause reporting, and specification update as dictated by ongoing customer projects and industrial standards. |
Direct Production and Supply of 3-Methacryloyloxy-4-Butyrolactone
We have specialized in the direct synthesis of 3-Methacryloyloxy-4-Butyrolactone for over a decade. Control over every process stage, from raw material selection through reaction, purification, and packaging, allows us to deliver material that meets the highest industry standards. Laboratories and production lines depend on the chemical stability and batch-to-batch reproducibility of this specialty methacrylate, and we make this consistency our top priority.
Industrial Applications Driving Demand
The versatility of 3-Methacryloyloxy-4-Butyrolactone attracts formulators across adhesives, advanced polymer development, and specialty coatings. Its ability to copolymerize with a wide range of acrylics and crosslinkers supports innovation in waterborne coatings, dental resins, photoresists, and UV-curable compositions. Resin manufacturers value its role in modifying toughness and adhesion, while electronics sectors adopt this monomer for developing photoresists and functional polymer films requiring thermal and chemical durability.
Controlling Production for Reliable Output
Tight controls at each manufacturing step underpin our product consistency. All incoming materials undergo verification before use. We utilize filtered reaction air supply, calibrated temperature control systems, and analytical instrumentation throughout the synthesis—returning quantitative HPLC and GC-MS results. Each lot receives complete retention samples and full certificate documentation. These controls limit variation, giving formulation chemists and production engineers confidence when scaling their own processes.
Scalable Packaging, Reliable Logistics
Our operation accommodates a range of packaging needs, from laboratory bottles to IBCs and steel drums. We invest in bulk storage systems and maintain vendor-managed inventory for customers operating just-in-time processes. Regional warehouses and stable logistics partnerships help minimize lead times to major production hubs in Europe, Asia, and North America. Our in-house packaging lines prevent contamination and ensure correct labeling, tamper-resistance, and secondary containment standards with every shipment.
Technical Support Backed by Experience
Customers developing new formulations regularly seek application guidance, troubleshooting, or performance validation. As producers, our technical team provides direct insights into chemical reactivity, storage stability, and formulation compatibility. Long-term experience means we understand the processing requirements in high-throughput industrial plants as well as research labs. Our lab staff work closely with partners to interpret analytical results, streamline raw material qualification, and help solve manufacturing challenges at scale.
Strengthening the Business Case for Industrial Buyers
By controlling production in-house, we offer dependable supply and stable pricing to manufacturers, distributors, and procurement groups. Traceability across every batch builds trust and supports regulatory filings for automotive, medical, and electronics end-uses. Our logistics flexibility shortens transitions between projects and tightens the alignment between chemical supply and downstream demand. With transparent quality control and responsive support, partners gain both predictable access to a critical specialty monomer and the confidence to expand their product pipelines.
Industrial FAQ
What is the purity and typical moisture content specification of 3-Methacryloyloxy-4-Butyrolactone supplied by your company?
Why Purity Makes a Difference at the Point of Use
In our production facility, purity is more than just a technical figure on a certificate. We know from decades of supplying specialty acrylic and methacrylate derivatives that even a fraction of a percent in impurity can cause unexpected variability in end-application properties. For 3-Methacryloyloxy-4-Butyrolactone, our qualified release technicians routinely achieve a minimum assay value of 98% by GC (area normalization with reference standard). Typical production lots fall within the 98.0% to 99.5% range, and our laboratory retains batch records and reference spectra for long-term traceability.
Our Approach to Moisture Control
Moisture sensitivity for this compound cannot be underestimated. Residual moisture above 0.20% (Karl Fischer) can trigger side reactions, causing color instability or unpredictable reactivity in downstream polymerizations. To address this, we monitor moisture at critical steps, including post-distillation, during repack, and just before shipment. Our average batch moisture content runs between 0.05% and 0.18%, verified with calibrated Karl Fischer titration. We only release material that meets or beats our maximum threshold of 0.20%. For customers needing even tighter moisture limits, our operators can arrange for additional vacuum treatment and provide documentation of final values.
How We Achieve Consistent Product Quality
Purity and moisture control do not come down to a single test during quality assurance. They depend on process discipline from raw material control through the handling of finished inventory. We use sealed glass-lined reactors and jacketed stainless steel tanks to minimize adventitious water uptake. Internal process audits cover valve integrity, nitrogen blanketing, and transfer line maintenance. Our operators check line flush records and filtration logs before every campaign. Sampling and testing of every production batch follow a detailed protocol that we have refined with input from both R&D and regular customers.
Practical Implications for Our Partners
Manufacturers that formulate UV-curable resins, adhesives, and coatings have contacted us to review cases where slight shifts in purity or water content altered their formulation performance. Some finishers noticed unexpected shifts in cure profiles or haze in clear coatings. Our team routinely shares best practices for storage—seal integrity, use of desiccant packs, and temperature control—to help reduce introduction of residual moisture after delivery. For larger consumers, we offer supply in nitrogen-purged drums with tamper-evident seals to provide added protection during transit and storage.
Commitment to Consistent Standards
We believe performance downstream starts at the source. Our technical documents reflect actual measured results and not guesswork. Customers who require product for regulated applications or unique formulations can request batch- or lot-specific analysis, and our technical team is available to discuss individual requirements in detail. We test each production lot without skipping steps that can compromise purity or leave unacceptable amounts of residual water.
Those demanding applications that depend on advanced acrylate chemistry require more than generic specifications or trust in third-party assurances. We stand behind our production and quality systems and make the results available to every customer who requests them. Each bottle, drum, or IBC leaving our plant reflects our direct responsibility—purity and moisture content measured, recorded, and delivered as promised.
What are the available packaging sizes and minimum order quantities for procurement of this product?
Fielding requests for details about packaging sizes and minimum order quantities has become a regular part of our day-to-day work on the manufacturing side. These questions reflect the reality of procurement for our customers. Understanding this information holds practical significance for planning budgets, scheduling logistics, and ensuring a smooth production line downstream. So let's walk through the practical considerations and share how we handle these matters at the factory level.
Packaging Options Born from Real Production Needs
Years of hands-on manufacturing taught us that packaging can influence everything from storage and shipping efficiency to material safety and site handling. Our core products typically leave the factory floor in industrial-strength bags, fiber drums, or Intermediate Bulk Containers. Each format has proven its value for different customer needs. The packaging type we recommend often depends on the characteristics of the product—dusting tendencies, sensitivity to moisture, and transport safety all factor in.
Standard bag sizes usually run from 25 kg to 50 kg. This weight fits most lift and material handling equipment in industry, minimizing strain and injury risk for unloading teams. Fiber drums range from 50 to 200 liters for solids or powders that require extra protection against exposure. When customers face large-scale, continuous processing or bulk blending, our Intermediate Bulk Containers (IBCs) are a preferred option. These typically hold about 1,000 liters, which keeps high-throughput lines moving and minimizes downtime from line changeovers.
Minimum Order Quantities—A Matter of Factory Efficiency
Minimum order quantities are never arbitrary from our side—they reflect what it takes for production to run efficiently. Setting these minimums helps us reduce handling losses, keep quality consistent from batch to batch, and avoid excessive partial packing, which risks contamination or waste. The typical guideline for our operation is a one-pallet minimum. For bagged product, this means a full pallet load—often 40 to 50 bags, totaling about 1,000 to 1,250 kg. Drum orders generally start at 4 to 8 drums per shipment, depending on drum size and transport constraints. Bulk containers follow the same logic—single IBC shipments are possible, but multiple units often travel together to cut freight costs and packaging waste.
Balancing Customer Needs with Production Consistency
On occasion, we field requests for non-standard packaging or smaller-than-usual order volumes. The production team treats these as special projects. Custom runs lead to line cleaning, repacking, or even switching out packaging types in mid-batch, which unavoidably increases lead time and overall cost. For critical projects, we can advise on the most practical packaging style and batch size that will work for both full-scale and pilot-scale customers. We also understand the just-in-time pressure many facilities face and do our best to optimize shipments where possible, but the core standards help maintain quality and cost-efficiency throughout our operation.
Continuous Improvement with Customer Feedback
Practical feedback from our long-term customers has helped us refine packaging and order policies. Issues such as shifting pallet loads, moisture ingress, and difficulty resealing opened drums pushed us to improve packaging integrity and labeling. We routinely review palletization schemes, test alternate packaging, and invest in automation to bring greater flexibility where justified by demand. Every new request gives us another data point for future improvements.
Direct feedback and communication help us stay responsive in delivering value—not just a commodity. By sharing details, clarifying restrictions, and listening carefully, we keep our production aligned with real-world application needs. Our doors—and our process improvement loop—stay open to collaborate on unique packaging or logistics challenges as markets evolve.
Is 3-Methacryloyloxy-4-Butyrolactone classified as a hazardous material for international shipping, and does it require any special documentation or certification for transport and import?
As a direct manufacturer of 3-Methacryloyloxy-4-Butyrolactone, we pay close attention to all critical aspects of international transport, including regulatory status under major freight classifications such as IATA, IMDG, and DOT. Shipping compliance starts with full knowledge of chemical hazard classification. The safety and regulatory standards exist to protect handlers, carriers, and recipients, and to keep shipments moving efficiently without regulatory delays.
Hazard Classification: What Our Tests and MSDS Show
Our laboratories have conducted a thorough review of the physical and chemical properties, along with acute toxicity thresholds, vapor pressure, and flammability. As standard, our MSDS and SDS documents provide the hazard classification aligned with the Globally Harmonized System (GHS). For 3-Methacryloyloxy-4-Butyrolactone, classification under international regulations revolves around its combination of functional groups: the methacrylate moiety (reactive, unsaturated ester) and the lactone ring (cyclical ester).
Across our recent batches, as supported by our accredited documentation, this compound does not fall under Class 3 (Flammable Liquids) or Class 6.1 (Toxic Substances) in the concentrations and packaging forms delivered by us. The boiling point, vapor pressure, and biohazard risks fall below the thresholds that typically trigger hazardous goods declarations under IATA, IMO, or ADR. That said, contamination, improper storage, or non-standard blending may alter these characteristics—and we control batch integrity closely to prevent this.
Certificate Requirements and Shipping Documentation
Even when a substance does not trigger mandatory hazardous good declarations, complete documentation stays critically important. Our logistics team attaches a full set of shipping documents for each consignment. These include our signed SDS, Certificate of Analysis (COA), packing list, invoice, and Certificate of Origin. Customs and import authorities in some regions ask for a GHS-compliant SDS, and we update this document according to the latest regulatory changes.
Clients sometimes ask if a Dangerous Goods Declaration (DGD) or UN Number accompanies the product. We confirm that no UN hazardous classification number applies to our specification of 3-Methacryloyloxy-4-Butyrolactone under the current regulations. Customs still request detailed descriptions and component breakdowns, especially for new chemical entities or first-time imports into a country. Our export compliance officers prepare all supporting paperwork directly from our production and QC records, reducing the risk of shipment rejection or port delays.
Transport Packaging and Risk Mitigation
We fill this product in sealed, UN-marked drums or high-density polyethylene containers, depending on shipment volume and destination. These packaging choices protect the integrity of the compound and prevent any accidental exposure. Each container is labeled according to GHS standards even for non-hazardous shipments. If a client’s destination country changes regulatory position, or if a carrier issues a new requirement, we keep our procedures agile and update documentation without disrupting supply timelines.
Our Approach to Global Compliance
Manufacturing chemicals for international shipment means staying ahead of both regulatory reforms and practical logistics. From production to port, our team maintains transparency about constituent risks and provides up-to-date evidence supporting transport classification. Importers and carriers receive original compliance statements, lab reports, and safety data directly from our technical staff. This approach limits disputes, delivers fast clearance, and protects the quality of product reaching our customers.
If your own import or quality teams require further verification, we can provide detailed technical documentation upon request. Our aim is to smooth the path for every overseas shipment by providing a complete, transparent supply chain from plant to delivery point.
Technical Support & Inquiry
For product inquiries, sample requests, quotations or after-sales support, please feel free to contact me directly via sales3@ascent-chem.com, +8615365186327 or WhatsApp: +8615365186327